RADIONUCLIDE IMAGING OF PRIMARY RENAL-CELL CARCINOMA BY 1-131-LABELED ANTI-TUMOR ANTIBODY

Google Scholar
  • 1 January 1978
    • journal article
    • research article
    • Vol. 19  (4) , 427-430
Abstract
A goat antibody against human renal-cell carcinoma reacted on immunofluorescence with renal-cell carcinomas from 20 patients, but not with normal adult human tissues, including kidney. After i.v. administration, the 131I-linked antibody showed preferential tumor localization in 6 of 7 patients with primary renal carcinoma. Labeled antitumor antibodies may have the specificity for tumor imaging that current radiopharmaceuticals lack.