A31P NMR Study of the Reaction of Adenosine 3′ 5′-Cyclic Monophosphate with 2, 4, 6-Triisopropylbenzenesulfonyl Chloride
- 1 September 1987
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 6 (4) , 785-792
- https://doi.org/10.1080/15257778708073424
Abstract
The reaction of adenosine 3′,5′-cyclic monophosphate (cyclic AMP) with 0.5–2.0 molar equivalents of 2,4,6-triisopropylbenzenesulfonyl (p-toluenesulfonyl or mesitylenesulfonyl) chloride leads to the rapid formation of the three possible phosphorus diastereoisomers [RPRP, SPSP and RPSP (SPRP)] of cyclic AMP symmetrical anhydride. The diastereoisomers were characterized by 31P NMR. The cyclic AMP sulfonic mixed anhydride could not be detected.This publication has 21 references indexed in Scilit:
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