Existence of Glucosaminyl Lactosyl Ceramide (Amino CTH-I) in Human Erythrocyte Membranes as a Possible Precursor of Blood Group-Active Glycolipids

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Abstract
A novel glycolipid containing N-acetylglucosamine (lacto-N-triose II ceramide, Amino CTH-I) was isolated as a minor component from the ceramide trihexoside fraction of human erythrocyte lipids. This glycolipid was purified by column chromatography and preparative high-speed liquid chromatography on Iatrobeads. Its structure was found to be N-acetylglucosaminyl(β1–3)galactosyl(β1–4)glucosyl-(β1–1)ceramide, so it is suggested that it may be a precursor of paragloboside and blood group-active glycolipids.