Base Induced Intramolecular Cyclization of Ã-Ketoimidoyl Chloride—An Efficient Preparation of 2-ACYL 5-Ethoxy Oxazoles
- 1 March 1996
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 26 (6) , 1149-1154
- https://doi.org/10.1080/00397919608003722
Abstract
The Ã-ketoimidoyl chlorides resulted from the reaction of acyl chlorides with ethyl isocyanoacetate provides 2-acyl 5-ethoxyoxazoles in moderate yields via a base-induced intramolecular cyclization.Keywords
This publication has 7 references indexed in Scilit:
- An efficient synthesis of Δ1-pyrrolines and related heterocycles via the base induced cyclocondensation of α-ketoimidoyl chlorides with electron deficient alkenesJournal of the Chemical Society, Chemical Communications, 1989
- Syntheses of 2-mercapto-4-substituted imidazole derivatives with antiinflammatory properties.CHEMICAL & PHARMACEUTICAL BULLETIN, 1984
- THIAZOLES FROM ETHYL ISOCYANOACETATE AND THIONO ESTERS: ETHYL THIAZOLE-4-CARBOXYLATEOrganic Syntheses, 1979
- Reaction of phthalic anhydrides with methyl isocyanoacetate: A useful synthesis of 1,2-dihydro-1-oxoisoquinolines.CHEMICAL & PHARMACEUTICAL BULLETIN, 1979
- A synthesis of 3-amino-4-hydroxyquinolin-2(1H)-one derivatives via oxazolo[4,5-c]quinolin-4(5H)-ones.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977
- Synthesis of amino acids and related compounds. 6. New convenient synthesis of .alpha.-C-acylamino acids and .alpha.-amino ketonesThe Journal of Organic Chemistry, 1973
- 2‐Unsubstituted Oxazoles from α‐Metalated Isocyanides and Acylating AgentsAngewandte Chemie International Edition in English, 1971