THE SYNDROME OF HYPONATREMIA AND RENAL SODIUM LOSS PROBABLY RESULTING FROM INAPPROPRIATE SECRETION OF ANTIDIURETIC HORMONE

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Abstract
A third case is reported of a patient with a bronchogenic carcinoma who developed profound hyponatremia and renal Na loss in the presence of normal kidneys and adrenal glands. The tenet has been set forth that such an unusual association is due to a prolonged and inappropriate secretion of antidiuretic hormone. It is hoped that future clinical studies of this syndrome may clarify the underlying mechanisms, particularly the possible elaboration of other humoral agents by the tumor.

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