A New and Efficient Method for the Selective Olefination of Aldehydes with Ethyl Diazoacetate Catalyzed by an Iron(II) Porphyrin Complex
- 14 December 2001
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (2) , 176-177
- https://doi.org/10.1021/ja016721v
Abstract
Olefination of aromatic and aliphatic aldehydes with ethyl diazoacetate was achieved in excellent yields with triphenylphosphine and catalytic amounts of iron(II) meso-tetra(p-tolyl)porphyrin. The reaction conditions are mild and the process is efficient and highly selective (>90%) for the synthesis of the trans-olefin isomer. Results of mechanistic studies are discussed.Keywords
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