Rate of Disappearance of Exogenous LH from the Blood in Mares1
- 1 August 1974
- journal article
- Published by Oxford University Press (OUP) in Journal of Animal Science
- Vol. 39 (2) , 397-403
- https://doi.org/10.2527/jas1974.392397x
Abstract
The disappearance rate in plasma of intravenously administered purified equine LH-131 I was studied in three anestrous mares. The calculated half-life of labeled LH was approximately 1 hr (58.9 ± 2.1 min.) during the first hour after injection and 4 to 5 hr. during the second and third hourly segments of the disappearance curve (261.8 ± 36.3 and 310.5 ± 14.2 min., respectively). The disappearance rate was significantly greater during the first hour than during the, next 2 hours. The disappearance rate for the second and third hours did not differ significantly. Similar disappearance rates were obtained in two additional experiments in which an equine pituitary fraction was given intravenously and the circulating levels of LH were determined by radioimmunoassay. The decrease in plasma LH was best characterized by a cubic regression line. Copyright © 1974. American Society of Animal Science . Copyright 1974 by American Society of Animal Science.Keywords
This publication has 0 references indexed in Scilit: