Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry
- 1 October 2008
- journal article
- Published by Elsevier in Analytica Chimica Acta
- Vol. 627 (1) , 105-111
- https://doi.org/10.1016/j.aca.2008.04.017
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- High-Throughput Mass Spectrometry Screening for Inhibitors of Phosphatidylserine DecarboxylaseSLAS Discovery, 2007
- High-Throughput Screening by Mass Spectrometry: Comparison with the Scintillation Proximity Assay with a Focused-File Screen of AKT1/PKBαSLAS Discovery, 2007
- Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primatesBiochemical and Biophysical Research Communications, 2005
- High Throughput Screening via Mass Spectrometry: A Case Study Using AcetylcholinesteraseASSAY and Drug Development Technologies, 2004
- The Role of Stearoyl-CoA Desaturase in Body Weight RegulationTrends in Cardiovascular Medicine, 2004
- Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinaseBiochemical Society Transactions, 2002
- A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening AssaysSLAS Discovery, 1999
- Conjugated Linoleic Acid Decreases Hepatic Stearoyl-CoA Desaturase mRNA ExpressionBiochemical and Biophysical Research Communications, 1998
- Accelerated essential fatty acid deficiency by Δ9 desaturase induction: dissociation between the effects on liver and other tissuesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
- Role of tyrosyl and arginyl residues in rat liver microsomal stearylcoenzyme A desaturaseBiochemistry, 1978