Synthesis, Biological, and Immunological Properties of Cyclic Peptides fromPlasmodium Falciparum Merozoite Surface Protein-1
- 10 July 2001
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 40 (14) , 2631-2635
- https://doi.org/10.1002/1521-3773(20010716)40:14<2631::aid-anie2631>3.0.co;2-6
Abstract
Effective structural mimics of a functionally important epitope from the malarial Merozoite Surface Protein-1 (MSP-1) include N-backbone cyclic peptides such as 1. They mimic the interaction of MSP-1 with human erythrocytes and can be used to induce parasite-specific monoclonal antibodies.Keywords
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