Antimalarial Activity of Tetrahydrohomopteroic Acid
- 23 June 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3782) , 1616-1617
- https://doi.org/10.1126/science.156.3782.1616
Abstract
Tetrahydrohomopteroic acid, an analog of tetrahydrofolic acid, shows antimalarial activity against Plasmodium cynomolgi and a pyrimethamine-resistant variant of this organism.This publication has 8 references indexed in Scilit:
- Folate Cofactor Biosynthesis by Plasmodium berghei. Comparison of Folate and Dihydrofolate as Substrates*The Journal of Protozoology, 1966
- The Synthesis of Homofolic Acid1—3The Journal of Organic Chemistry, 1965
- The Enzymatic Synthesis of Folate-like Compounds from Hydroxymethyldihydropteridine PyrophosphateJournal of Biological Chemistry, 1964
- Tetrahydrohomofolate, a Specific Inhibitor of Thymidylate SynthetaseJournal of the American Chemical Society, 1964
- The Biosynthesis of Folic AcidPublished by Elsevier ,1961