Complexes of Stannous Fluoride and Other Group IVB Dihalides with Mammalian Hemoproteins
- 30 September 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 197 (4311) , 1376-1378
- https://doi.org/10.1126/science.897674
Abstract
Stannous fluoride, the widely used anticaries toothpaste additive, and other tin and germanium dihalides form complexes with hemoproteins such as hepatic cytochrome P-450, hemoglobin, and peroxidase. These complexes are characterized by visible spectra closely similar in shape, molar absorptivity, and absorbance maxima to those obtained with analogous complexes of carbon monoxide. Evidence is presented that the observed complexes are formed with uncharged MX2 or LMX2, moieties (where L is a neutral Lewis base, M is a metal, and X is a halogen) acting as pi-acceptor ligands.This publication has 17 references indexed in Scilit:
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