In vitrosusceptibility ofCryptococcus neoformansto steroids

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Abstract
The inhibitory effect of estradiol, norethynodrel, progesterone, testosterone and diethylstilbestrol on 7 human isolates of C. neoformans was determined. Northynodrel, progesterone or testosterone had no apparent effect on their growth. Diethylstilhestrol at a concentration of 10 μg/ml completely suppressed the growth of all isolates and estradiol at a concentration of 1·0 μg/ml completely suppressed the growth of 3 isolates and moderately inhibited the remainder.