Factors Associated with Incomplete Virological Response to Highly Active Antiretroviral Therapy
Open Access
- 1 February 2000
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 30 (2) , 407-408
- https://doi.org/10.1086/313670
Abstract
Sir—We read with interest the article by Clough et al. [1] concerning factors that predict incomplete virological response to protease inhibitor—based antiretroviral therapy. This retrospective study included 104 HIV-positive adults, most of whom had previously received antiretrovirals. Logistic regression analysis of predictors of incomplete response to protease inhibitor—based antiretroviral therapy (defined as a viral load >400 copies/mL after 20 weeks of therapy) included low baseline weight, baseline plasma HIV type 1 RNA level, prophylaxis for Pneumocystis carinii pneumonia, and active drug abuse. Regular prescription of narcotics or benzodiazepine anxiolytics and use of any Internet site predicted a more favorable response.Keywords
This publication has 1 reference indexed in Scilit:
- Factors That Predict Incomplete Virological Response to Protease Inhibitor‐Based Antiretroviral TherapyClinical Infectious Diseases, 1999