Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
- 1 October 1998
- journal article
- research article
- Published by Elsevier in Current Biology
- Vol. 8 (21) , 1195-S1
- https://doi.org/10.1016/s0960-9822(07)00493-9
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Cancer predisposition: Where's the phosphate?Current Biology, 1998
- Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domainProceedings of the National Academy of Sciences, 1997
- Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-KinaseScience, 1997
- Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancersNature Genetics, 1997
- PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate CancerScience, 1997
- PI3K: Downstream AKTion Blocks ApoptosisCell, 1997
- Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.Proceedings of the National Academy of Sciences, 1996
- Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomasInternational Journal of Cancer, 1995
- Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma.Proceedings of the National Academy of Sciences, 1987
- Radiation therapy for neoplasms of the brainJournal of Neurosurgery, 1987