Immunological and gadolinium-DTPA MRI evaluation of relapsing remitting multiple sclerosis
- 1 October 1992
- journal article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 86 (4) , 342-345
- https://doi.org/10.1111/j.1600-0404.1992.tb05098.x
Abstract
The levels of lymphocytes, blood lymphocytes subsets (CD3+, CD4+, CD8+, DR+, CD25+, CD4+, CD45RA+, CD4+, CD29+ cells) and sIL-2r of 10 patients affected by relapsing-remitting multiple sclerosis were serially studied. The identification of the activity of the disease was made by gadolinium-DTPA (Gd-DTPA) MRI. The immunological determinations and the MRI of the brain and spinal cord were performed every 14th day for a period of three months. No significant difference of the immunological values were found between the presence and the absence of Gd-DTPA enhancing areas, except lymphocytes (p < 0.05). These immunological parameters, evaluated in the peripheral blood, are not a marker of disease activity in relapsing-remitting MS patients.Keywords
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