Prefrontal dysfunction and treatment response in geriatric depression.
Open Access
- 1 August 1999
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 56 (8) , 713-718
- https://doi.org/10.1001/archpsyc.56.8.713
Abstract
FRONTOSTRIATAL dysfunction occurs in some patients with major depression. Depression is frequent in disorders of subcortical structures.1 Disturbances in planning, sequencing, organizing, and abstracting have been reported in late-onset depression2 and are similar to those occurring in Huntington disease.3 Memory impairment resembling subcortical dementia often occurs in geriatric depression.4Keywords
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