Glycolysis in Films of Oral Samples from Persons with Different Caries Rates

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Abstract
Rates of glycolysis were studied in thin films of oral samples from children with high or low susceptibility to dental caries to discover what parameter of glycolysis rates might be correlated with caries rates. There was a great similarity between sediment obtained by chewing paraffin and by toothbrushing. No indication was obtained for the presence of a glycolysis-stimulating or -inhibiting factor in the supernatant liquid from either the caries-resistant or -susceptible groups. In treatments with strong and weak solutions of glucose and sucrose, the stronger solution and longer contact increased the magnitude of pH drop and the duration of the pH depression. There was greater pH depression with sucrose. None of the measures of glycolysis rates were diagnostic of the dental caries attack rate of the subject.