DNA Marker D11S384 Shows Zero Recombination with the Ataxia-telangiectasia Locus in North American Families
- 1 January 1994
- journal article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 66 (6) , S67-S69
- https://doi.org/10.1080/09553009414551881
Abstract
At the genetic locus D11S384, one probe detects a Taq1 RFLP and another detects a RFMP. In 52 pedigrees of North American A-T patients, parental haplotypes based on these two bi-allelic systems have a heterozygosity of 0·69 and a PIC of 0·64. No recombinant events between D11S384 and the A-T locus were detected in the 43 pedigrees in which this marker locus was informative.Keywords
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