The NMDA Receptor

Abstract
This book comprises coverage of the NMDA receptor. The NMDA receptor is an important protein in the brain, which is involved in physiological processes such as synaptic transmission and synaptic plasticity, which may underlie learning and memory. Pathological changes involving the NMDA receptors probably contribute to the development of epilepsy, acute neuronal damage such as that resulting from stroke and chronic neuropathologies such as Alzheimer's disease. There is considerable interest in the development of pharmacological agents active at NMDA receptors as new therapeutic agents. Each cha ... More This book comprises coverage of the NMDA receptor. The NMDA receptor is an important protein in the brain, which is involved in physiological processes such as synaptic transmission and synaptic plasticity, which may underlie learning and memory. Pathological changes involving the NMDA receptors probably contribute to the development of epilepsy, acute neuronal damage such as that resulting from stroke and chronic neuropathologies such as Alzheimer's disease. There is considerable interest in the development of pharmacological agents active at NMDA receptors as new therapeutic agents. Each chapter in this book covers developments in the molecular biology and the molecular pharmacology of the NMDA receptor.

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