FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug resistance
Open Access
- 15 October 2009
- journal article
- research article
- Published by Springer Nature in Malaria Journal
- Vol. 8 (1) , 229
- https://doi.org/10.1186/1475-2875-8-229
Abstract
A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider implementation of these tools is the absence of practical methods enabling high throughput analysis. Here a new Zip-code array is described, called FlexiChip, linked to a dedicated software program, which largely overcomes this problem.This publication has 21 references indexed in Scilit:
- Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in NigerMalaria Journal, 2009
- Rapid Microarray-Based Method for Monitoring of All Currently Known Single-Nucleotide Polymorphisms Associated with Parasite Resistance to Antimalaria DrugsJournal of Clinical Microbiology, 2007
- World Antimalarial Resistance Network (WARN) III: Molecular markers for drug resistant malariaMalaria Journal, 2007
- The rationale and plan for creating a World Antimalarial Resistance Network (WARN)Malaria Journal, 2007
- A genome-wide scalable SNP genotyping assay using microarray technologyNature Genetics, 2005
- Normalization of cDNA microarray dataMethods, 2003
- pfcrt Polymorphism and Chloroquine Resistance in Plasmodium falciparum Strains Isolated in CambodiaAntimicrobial Agents and Chemotherapy, 2003
- DNA microarrays for malariaTrends in Parasitology, 2002
- A Molecular Marker for Chloroquine-Resistant Falciparum MalariaNew England Journal of Medicine, 2001
- Universal DNA microarray method for multiplex detection of low abundance point mutationsJournal of Molecular Biology, 1999