Effect of bilateral hippocampal ablation on DRL performance.

Abstract
Six rats with bilateral hippocampal lesions, 6 rats with neocortical destruction, and 5 normal rats were conditioned to bar press on CRF (continuous reinforcement) and then on DRL (differential reinforcement of low rate) schedules of water reinforcement. In comparison with the neodecorticate and normal Ss, the hippo-campectomized Ss showed lower rates of responding under CRF, higher rates under DRL, and, therefore, a lower percentage of reinforced responses under DRL.