Trimethoprim resistance in urinary tract pathogens in two Nigerian hospitals
Open Access
- 1 January 1989
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Antimicrobial Chemotherapy
- Vol. 23 (1) , 151-154
- https://doi.org/10.1093/jac/23.1.151
Abstract
One hundred and twenty eight (63·3%) of 202 isolates of Gram-negative bacilli from urinary infections in patients in two Nigerian hospitals were found to be resistant to trimethoprim. Of the trimethoprim-resistant organisms, 111 (86·7%) showed MICs of trimethoprim in excess of 1000 mg/l. Trimethoprim resistance was found to be transferable from 65 (50·8%) of these highly resistant organisms into Escherichia coli EC1005. The trimethoprim-resistant strains obtained in the study were also resistant to at least one other antibiotic of the nine tested.Keywords
This publication has 1 reference indexed in Scilit:
- Characterization of trimethoprim resistance by use of probes specific for transposon Tn7Antimicrobial Agents and Chemotherapy, 1984