A Genetic Model of Narcolepsy
- 1 March 1976
- journal article
- Published by Royal College of Psychiatrists in The British Journal of Psychiatry
- Vol. 128 (3) , 276-279
- https://doi.org/10.1192/bjp.128.3.276
Abstract
Summary: An analysis of recently published family history data on rapid eye movement (REM) narcolepsy was undertaken to determine the goodness-of-fit of a multifactorial (MF) model of inheritance. The analysis revealed that a two-threshold MF model can successfully account for the prevalence of REM narcolepsy and other disorders of excessive sleep (DES) observed in the first-degree relatives of the REM narcoleptic probands studied.Keywords
This publication has 12 references indexed in Scilit:
- The Multifactorial Model of Disease Transmission: I. Description of the Model and its use in PsychiatryThe British Journal of Psychiatry, 1975
- A FAMILY STUDY OF 50 REM NARCOLEPTICSActa Neurologica Scandinavica, 1974
- The use of multiple thresholds in determining the mode of transmission of semi‐continuous traits*Annals of Human Genetics, 1972
- The inheritance of liability to certain diseases, estimated from the incidence among relativesAnnals of Human Genetics, 1965
- NARCOLEPSY AND OTHER DISTURBANCES IN THE SLEEP-WAKING RHYTHMJournal of Nervous & Mental Disease, 1963
- Nocturnal sleep of narcolepticsElectroencephalography and Clinical Neurophysiology, 1963
- NARCOLEPSY IN IDENTICAL TWINSJournal of Neurology, Neurosurgery & Psychiatry, 1961
- ON NARCOLEPSY: I. FAMILIAL NARCOLEPSEYActa Psychiatrica Scandinavica, 1942
- Zum Ersatz des Weinbergschen “abgekürzten Verfahrens“Zeitschrift für die gesamte Neurologie und Psychiatrie, 1935