THE EFFECT OF PENICILLIN ON THE RENAL LESIONS OF SUBACUTE BACTERIAL ENDOCARDITIS
- 1 April 1952
- journal article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 36 (4) , 1086-1089
- https://doi.org/10.7326/0003-4819-36-4-1086
Abstract
The use of antibiotics, in particular penicillin, in the treatment of subacute bacterial endocarditis has so altered the course of the disease that infection is arrested in all but 10 per cent of cases treated. Only about 10 to 20 per cent die from the complications of the disease itself. The exact rôle of the renal lesions as a cause of death in treated cases of subacute bacterial endocarditis is still not settled. A report by Christie1 on 269 patients treated with penicillin listed 73 deaths of which 8 were due to uremia. However, in a study by Pillsbury andKeywords
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