Effects of Lymphoid Cells and Serum on Target Cells in Xenogeneic Cell-Culture Systems
- 1 July 1970
- journal article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 134 (3) , 744-747
- https://doi.org/10.3181/00379727-134-34874
Abstract
Spleen lymphocytes of rabbits immunized with KB cells brought about destruction of these cells in tissue culture. No such effect was seen with normal lymphocytes. Immune sera from these rabbits reacted with KB cells in CF, CT, and SGI tests. The reaction was found to be specific as these sera did not react with cells of human amnion or of hamster tumors induced by adenovirus type 12. Anti-KB serum did react, however, with cells derived from fetal human skin.Keywords
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