High-Dose Recombinant Human Erythropoietin and Low-Dose Corticosteroids for Treatment of Anemia in Paroxysmal Nocturnal Hemoglobinuria
- 1 January 1994
- journal article
- case report
- Published by S. Karger AG in Acta Haematologica
- Vol. 91 (2) , 62-65
- https://doi.org/10.1159/000204254
Abstract
Three patients with paroxysmal nocturnal hemoglobinuria (PNH) and severe anemia were treated with high-dose recombinant human erythropoietin (rHEpo) and low-dose corticosteroids. During therapy their hemoglobin levels gradually improved and no blood transfusions were required. Neither rHEpo nor corticosteroids caused any side effects. This study shows that high rHEpo and low corticosteroid doses may improve the anemia of PNH patients.Keywords
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