Demonstration of Glucagon in the Stomach of Human Fetuses
Open Access
- 1 October 1981
- journal article
- Published by American Diabetes Association in Diabetes
- Vol. 30 (10) , 879-882
- https://doi.org/10.2337/diab.30.10.879
Abstract
Electron microscopy using antiglucagon or antiglicentin antisera and the protein A-gold (pAg) technique revealed a population of immunoreactive cells in the gastric mucosa of human fetuses. The secretory granules of these cells showed the same ultrastructural characteristics and the same labeling pattern as pancreatic α-granules. These data demonstrate that the stomach of human fetuses contains cells with secretory granules indistinguishable by morphologic and immunocytochemical criteria from the pancreatic Acells.Keywords
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