How Many Different Viruses Causing Leukemia in Mice?

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Abstract
It appears that a single virus, designated "Mouse Leukemia Virus Type A", is responsible for the induction of various forms of leukemia and lymphomas in mice. Most of the leukemic viruses recently isolated in mice from a variety of sources, such as from spontaneous leukemia, from radiation-induced leukemia, or from different transplanted mouse tumors, may represent isolations from different sources of the same leukemic virus, i. e. of the mouse leukemia virus type A, or at best some of its close variants. The different leukemogenic virus strains isolated from a variety of sources induce in mice morphologically the same disease. It is quite possible that there may exist slight antigenic differences between at least some of the variant strains of the mouse leukemia virus. Such differences do not necessarily imply that the isolated strains represent distinct viruses.

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