Adolescent asthma after rhinovirus and respiratory syncytial virus bronchiolitis

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Abstract
Background and Aims Asthma risk is increased after bronchiolitis in infancy. Recent studies have suggested that the risk may be dependent on the causative virus. The aim of the study was to evaluate the asthma risk in adolescence in subjects hospitalized for rhinovirus or respiratory syncytial virus (RSV) bronchiolitis in infancy. Subjects and Methods At the median age of 16.5 years, a questionnaire was sent to 96 study subjects hospitalized for bronchiolitis at P = 0.023, mixed infections included; 81.3% vs. 50%, P = 0.067, mixed infections excluded). Conclusions Patients hospitalized for RSV and rhinovirus bronchiolitis at <24 months of age had an increased asthma risk at 15–18 years of age compared with population controls. Within the former bronchiolitis group, the risk of self-reported asthma was higher after non-RSV versus RSV and after rhinovirus versus non-rhinovirus bronchiolitis. Pediatr Pulmonol. 2013; 48:633–639.
Funding Information
  • Kuopio University Hospital (440071)
  • The National Foundation for Pediatric Research in Finland
  • The National Graduate School of Clinical Investigation in Finland
  • The Kerttu and Kalle Viik's Foundation

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