Upper Tract Tumours in Patients with Vesico-Ureteral Reflux and Recurrent Bladder Tumours

Abstract
Twenty-seven patients with recurrent low-grade, low-stage transitional cell carcinoma (TCC) of the bladder and unior bilateral vesico-ureteral reflux were followed for up to 18 yr in order to study a possible higher incidence of TCC of the upper tract. No patients developed tumor of the upper collecting system during the follow-up period. Routine bladder instillations with Thiotepa may be 1 explanation of such a finding.

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