Synthese von rac‐4′‐O‐Methylglabridin, einem antimikrobiellen prenylierten Isoflavan aus Glycyrrhiza glabra L.

Abstract
Synthesis of rac‐4′‐O‐Methylglabridin, an Antimicrobial Prenylated Isoflavan from Glycyrrhiza glabra L.A synthesis of racemic ‐4′‐O‐methylglabridin (1) is described. The key steps are the transformation of the isoflavan‐4‐one 4 into a dithioacetal 5 followed by desulfuration with Raney nickel.