The Error Hypothesis of Mutation
- 11 March 1960
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 131 (3402) , 730
- https://doi.org/10.1126/science.131.3402.730
Abstract
Accumulation of mutants in glucose-limited chemostats is proportional to growth rate, while in tryptophan-limited chemostats it is independent of growth rate. This behavior, which implies the failure of the error hypothesis, may be explainable on the basis of a unitary hypothesis: the results with glucose may be due to reversion or loss of latent mutants.Keywords
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