Human placental lipid metabolism. III. Synthesis and hydrolysis of phospholipids
- 1 September 1967
- Vol. 2 (5) , 403-405
- https://doi.org/10.1007/bf02531854
Abstract
Both diacyl GPC (glycerylphosphorylcholine) and diacyl GPE (glycerylphosphorylethanolamine) are synthesized in human placental tissue from their respective monoacyl precursors. The origin of the monacyl phosphatides is apparently not the result of placental phosphatide acyl-hydrolase activity. The most likely source is maternal serum. The declining level of 1-acyl GPC in maternal serum is not attributable to lysophosphatide acylhydrolase activity and is probably explained by placental utilization for the synthesis of diacyl GPC.Keywords
This publication has 12 references indexed in Scilit:
- The role of placenta in lysolecithin metabolism in rats and miceBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1967
- Human placental lipid metabolism. I. Synthesis of phosphatidylcholine from lysophosphatidylcholine.1966
- HUMAN PLACENTAL LIPID METABOLISMPublished by American Academy of Pediatrics (AAP) ,1966
- Lecithinase and lysolecithinase activity in rat tissuesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1966
- Metabolism of red-cell lipids II. Conversions of lysophosphoglyceridesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1965
- Plasma Lipid Fractions, Including Individual Phospholipids, at Various Stages of PregnancyActa Medica Scandinavica, 1965
- Metabolism of phospholipids in normal and spherocytic human erythrocytesJournal of Lipid Research, 1964
- Die Aktivität der Phosphatidase A und der Lysophosphatidase in Placenta, mütterlicher und foetaler Leber bei trächtigen RattenThe Science of Nature, 1964
- The Enzymatic Conversion of Phospholipid Ethanolamine to Phospholipid Choline in Rat LiverJournal of Biological Chemistry, 1961
- THE ORIGIN OF FETAL LIPIDSCold Spring Harbor Symposia on Quantitative Biology, 1954