SERUM LYSOZYME ACTIVITY IN CHILDREN WITH HEMATOLOGICAL AND MALIGNANT DISORDERS

1 December 1975

journal article
Published by Wiley in Acta Paediatrica

Vol. 64 (6) , 830-832
https://doi.org/10.1111/j.1651-2227.1975.tb03932.x

Abstract

Pretreatment serum lysozyme activity was high in 2 children with myelomonocytic leukemia, 800 and 1 000 mug/ml, normal in all 10 cases of acute lyelocytic leukemia and subnormal in 21 of 34 cases of acute lymphocytic leukemia. Normal values were found in all but one case of acute lymphocytic leukemia during complete remission including 8 cases after all therapy had been discontinued. All 8 are still in complete remission. Low serum lysozyme activity was found in 5 patients with acute lymphocytic leukemia in complete relapse, this could possibly be helpful in the diagnosis of early relapse. Activity was subnormal in 5 of 17 children with malignant tumours, and in 3 of 65 cases of various benign hematological disorders.

Keywords

This publication has 4 references indexed in Scilit:

LYSOZYMES IN FECES FROM INFANTS AND CHILDREN
Acta Paediatrica, 1974
Lysozyme in Leukemia
Medical Clinics of North America, 1973
Serum muramidase levels in acute leukemia
The Lancet Healthy Longevity, 1972