CENTRIC FUSION OF AUTOSOMAL CHROMOSOMES IN A BITCH AND OFFSPRING

  • 1 January 1978
    • journal article
    • research article
    • Vol. 39  (5) , 861-864
Abstract
A fertile Golden Retriever cross had a chromosome number of 77, with 3 large metacentric chromosomes representing the 2 X chromosomes and a centric fusion of 2 autosomes. The known reproductive history of the bitch included litters of 6, 5, 13 and 10 pups during 4 consecutive estrous cycles. A total of 16 pups and their sire were located and karyotyped. The sire and 9 of the pups were of normal karyotype. Seven of the 16 pups were found to be carriers of the translocation. The translocation was determined to be a fusion of chromosomes 13 and 17, utilizing G[giemsa]-banding techniques. Although centric fusion has been reported in dogs with congenital disease, the dogs in the present study were not phenotypically unique or abnormal.

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