PROGNOSTIC VALUE OF PREGNANCY ZONE PROTEIN DURING EARLY-PREGNANCY IN SPONTANEOUS-ABORTION

  • 1 January 1978
    • journal article
    • research article
    • Vol. 51  (6) , 677-681
Abstract
The concentration of pregnancy zone (PZ) protein in maternal serum during early normal pregnancy was followed in a prospective study of 261 pregnant women. A marked increase which followed an exponential function was found and a theoretic onset of induction at the time for implantation was calculated. Women with a later spontaneous abortion had low values. The prognostic relevance of PZ determinations was studied and values from women who later had a spontaneous abortion were compared to those from normal pregnancies. The prognostic value of PZ protein was compared to that of hCG [human chorionic gonadotropin] and progesterone. PZ and hCG assays had the same prognostic accuracy concerning the outcome of pregnancy while determinations of progesterone were less valuable.

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