Non‐islet cell tumour induced hypoglycaemia with acromegaloid facial and aral swelling
- 1 April 1995
- journal article
- case report
- Published by Wiley in Clinical Endocrinology
- Vol. 42 (4) , 433-435
- https://doi.org/10.1111/j.1365-2265.1995.tb02654.x
Abstract
The syndrome of non-islet cell tumour hypoglycaemia (NICTH) has been linked with the synthesis and secretion of 'big' IGF-II. We report a patient with a large pelvic clear cell sarcoma who developed recurrent severe hypoglycaemia and in addition presented with severe soft tissue facial swelling, skin tags and nuchal hyperpigmentation. After resection of the tumour serum 'big' IGF-II returned to normal and the acromegaloid skin changes remitted.Keywords
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