CITRX thioredoxin is a putative adaptor protein connecting Cf‐9 and the ACIK1 protein kinase during the Cf‐9/Avr9‐ induced defence response
- 5 July 2006
- journal article
- Published by Wiley in FEBS Letters
- Vol. 580 (17) , 4236-4241
- https://doi.org/10.1016/j.febslet.2006.06.077
Abstract
Tomato Cf-9, a receptor-like protein (RLP), confers resistance to races of the fungal pathogen Cladosporium fulvum that express the Avr9 avirulence gene. CITRX (Cf-9-interacting thioredoxin) was previously identified in a yeast two-hybrid screen as a protein interacting with the cytoplasmic domain of Cf-9 and shown to be a negative regulator of the cell death induced after Cf-9/Avr9 interaction. ACIK1 is a Ser/Thr protein kinase that is specifically required for the Cf-9 and Cf-4 dependent defence response in tomato. In this paper we present data suggesting that CITRX may act as an adaptor recruiting the ACIK1 kinase to the cytoplasmic domain of Cf-9 upon elicitation with the Avr9 peptide. Interestingly, the catalytic activities of both CITRX and ACIK1 are not required for their interaction.Keywords
This publication has 37 references indexed in Scilit:
- The U-Box Protein CMPG1 Is Required for Efficient Activation of Defense Mechanisms Triggered by Multiple Resistance Genes in Tobacco and TomatoPlant Cell, 2006
- Phylogenomic Analysis of the Receptor-Like Proteins of Rice and ArabidopsisPlant Physiology, 2005
- Functional Analysis ofAvr9/Cf-9 Rapidly ElicitedGenes Identifies a Protein Kinase, ACIK1, That Is Essential for Full Cf-9–Dependent Disease Resistance in TomatoPlant Cell, 2005
- A Patch of Surface-Exposed Residues Mediates Negative Regulation of Immune Signaling by Tomato Pto Kinase[W]Plant Cell, 2004
- Arabidopsis Downy Mildew Resistance Gene RPP27 Encodes a Receptor-Like Protein Similar to CLAVATA2 and Tomato Cf-9Plant Physiology, 2004
- Control of Stomatal Distribution on the Arabidopsis Leaf SurfaceScience, 2002
- Retracted: An ∼400 kDa membrane‐associated complex that contains one molecule of the resistance protein Cf‐4The Plant Journal, 2002
- Receptor-like kinases from Arabidopsis form a monophyletic gene family related to animal receptor kinasesProceedings of the National Academy of Sciences, 2001
- Plant pathogens and integrated defence responses to infectionNature, 2001
- The tomato gene Pti1 encodes a serine/threonine kinase that is phosphorylated by Pto and is involved in the hypersensitive responseCell, 1995