The Cutaneous Basophil Response to Mitogens

Abstract
Basophil-rich skin reactions have been elicited in normal guinea pigs with local injections of phytohemagglutinin, concanavalin A, and pokeweed mitogen. Escherichia coli lipopolysaccharide, a B cell mitogen, had no such effect. These results suggest that T cells may mediate such reactions by releasing a factor chemotactic for basophils.

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