Immunoglobulins in Haemolytic Disease of the Newborn

Abstract
Concentrations of IgG, IgA and IgM were measuredin the sera of infants with haemolytic disease of the newborn and I control infants from birth to the age of 6 months. No significant Differences were found between the IgG, IgA and IgM concentrations in haemolytic disease and control infants of comparable birth weight. Inhibition of IgG synthesis in the infant from the presence of antiglobulins in transfused blood or from interference with a feed-back control mechanism based on Gm phenotype could not be demonstrated.

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