A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE
Open Access
- 1 March 1970
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 44 (3) , 476-483
- https://doi.org/10.1083/jcb.44.3.476
Abstract
HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G1, S, and G2 portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments. The results indicated that some of the HnRNA molecules were equivalent at all times in the cell cycle, but limitations in the sensitivity of the hydridization reactions, as well as in the spectrum of hybridizing molecules, restrict the conclusions that can be drawn from these comparisons.Keywords
This publication has 19 references indexed in Scilit:
- Molecular weights of some HeLa ribosomal RNA'sJournal of Molecular Biology, 1969
- Synthesis of DNA-like RNA in synchronized cultures of mammalian cellsBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1968
- RNA SYNTHESIS IN CHINESE HAMSTER CELLSThe Journal of cell biology, 1968
- Cyclic Changes in Enzyme Activity in Synchronized Mammalian Cell CulturesScience, 1968
- The effects of methionine deprivation on ribosome synthesis in HeLa cells.Proceedings of the National Academy of Sciences, 1967
- THE CYTOPLASMIC SYNTHESIS OF HISTONES IN HELA CELLS AND ITS TEMPORAL RELATIONSHIP TO DNA REPLICATIONProceedings of the National Academy of Sciences, 1967
- Methylation of 45 s ribosomal RNA precursor in HeLa cellsJournal of Molecular Biology, 1967
- Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytesJournal of Molecular Biology, 1966
- Synthesis of Ribosomal RNA in Synchronized Hela CellsNature, 1965
- POLYRIBOSOMES IN NORMAL AND POLIOVIRUS-INFECTED HELA CELLS AND THEIR RELATIONSHIP TO MESSENGER-RNAProceedings of the National Academy of Sciences, 1963