Diffusely Increased Tc-99m-MDP Uptake in Both Kidneys

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Abstract
Patients with diffusely increased uptake in both kidneys (hot kidneys) on 99mTc-methylene diphosphonate bone imaging were evaluated. Among 2056 patients reviewed, this finding was seen in 13 patients (0.63%): 4 with liver cirrhosis, 2 with lung cancer, 1 each with primary hepatoma, Hodgkin''s disease, malignant lymphoma, thyroid cancer, leukemia, sideroblastic anemia and diabetes mellitus. Renal vascular disease and Fe overload are considered to be the major causes of this finding.

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