Evaluation of the annual killifish Nothobranchius guentheri as a tool for rapid acute toxicity screening
- 1 October 1999
- journal article
- research article
- Published by Oxford University Press (OUP) in Environmental Toxicology and Chemistry
- Vol. 18 (10) , 2258-2261
- https://doi.org/10.1002/etc.5620181020
Abstract
This study evaluated the use of Nothobranchius guentheri as a novel organism for rapid acute toxicity screening. A major advantage of the species is that there is no need to maintain a continuous culture to have organisms immediately available for testing. Rather, the embryos are viable under long—term storage conditions and can be hatched within a few hours. The tests require only 24 h with standard laboratory equipment. Sensitivity levels for 11 representative toxicants were comparable to those reported for five of the standard U.S. Environmental Protection Agency test species requiring continuous culture.Keywords
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