Utilization of the deuterium isotope effect to suppress enolization during alkylation of ketones
- 1 January 1981
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 23,p. 1215-1216
- https://doi.org/10.1039/c39810001215
Abstract
A substantial enhancement in yield is observed in the reaction of enolizable ketones with the lithium salt of N,N-diethylbenzamide and N,N-diethyl-1-naphthamide when the hydrogen atoms α to the carbonyl group are replaced with deuterium.Keywords
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