Some Pharmacological Aspects of a Toxic Substance from Oocysts of the Coccidium Eimeria tenella

Publisher Website
Google Scholar
Abstract
Toxic substances from the oocysts of the coccidium, Eimeria tenella, produced death when injected intravenously into rabbits. The following effects were observed in pharmacological investigations with this substance in the rabbit; an immediate drop in blood pressure with a subsequent increase followed by a marked increase in pressure just prior to death; abnormalities in ecg tracings, principally inversion of the T wave, distortion of the QRS complex, and absence of the P wave at respiratory arrest; pyrogenic responses resulting in elevated body temperature; hyperglycemia followed by hypoglycemia and blood-sugar depletion at death.