Ultrastructural Features of Skeletal Muscle Differentiation and Development

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Abstract
It is obvious from even this cursory review that ultrastructural studies have provided the basis for much of our existing knowledge about differentiation and development of muscle. It is also evident that a great deal is known about differentiation of muscle cells. Because the major myofibrillar proteins of muscle are well characterized and possess unique features that permit their isolation and identification from very small amounts of tissue, muscle tissue may well constitute a very favorable system for the study of cell differentiation in general. It seems probable that future progress in the study of muscle differentiation will rely on an integrated application of biochemical, immunological, and ultrastructural techniques. Information from such efforts should eventually lead to the ability to control the rate of synthesis of myofibrillar proteins, and the rates and times at which myoblasts fuse to form muscle cells. Possession of this ability will make it possible to achieve extraordinary increases in feed efficiency and muscling in our domestic animals, and indeed, may usher in an entirely new era in animal science. Copyright © 1974. American Society of Animal Science . Copyright 1974 by American Society of Animal Science.

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