Effect of Formulation Components on Drug Release from Multiparticulates
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 20 (20) , 3207-3236
- https://doi.org/10.3109/03639049409041974
Abstract
The effect of excipients on the release of drug from multiparticulates or pellets coated and uncoated prepared by the extrusion/spheronization and centrifugal processes is reviewed in this paper. A processing viewpoint has been taken because of the relationship between a rugged scaleable process and reliable excipients. Only aqueous coating dispersions have been reviewed because of their increasing usage due to environmental and cost reduction programs.Keywords
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