Toxicologic studies in growing sheep fed silage corn cultured on municipal sludge‐amended acid subsoil

Abstract
Field corn was grown on subsoil, pH 5.5, that had been amended with 100 dry tons/acre (224 metric tons/ha) of municipal sewage sludge from Syracuse, New York [USA]. The corn plants containing 3.88 ppm dry wt Cd were field-chopped and ensiled, and the silage was fed to growing sheep for 225 days. The sheep fed the sludge-grown corn silage showed a significantly higher feed efficiency, higher hepatic microsomal p-nitroanisole O-demethylase activity, and higher concentrations of Cd in liver and kidney and Ni in kidney as compared to controls. No significant treatment effects were observed in mutagenic responses for animal feed or feces samples. No consistent treatment effects were noted during histopathologic examination.

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