Tropheryma whippleiCirculating in Blood Monocytes

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Abstract
Whipple's disease is an infection that affects primarily the intestine, but some cases involve the heart valve, the peripheral lymph nodes, the joints, and the central nervous system.1 Recently, the establishment of Tropheryma whipplei (formerly T. whippelii, the causative agent of Whipple's disease)2 in culture allowed the generation of antibodies against the bacterium3 that we used for immunostaining the valve2 or duodenal specimen3 of infected patients. Here, we report the immunodetection of T. whipplei in the circulating monocytes of a patient with untreated Whipple's disease.

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