Hyperlactataemia in Phenformin-treated Diabetics
- 22 January 1972
- Vol. 1 (5794) , 205-206
- https://doi.org/10.1136/bmj.1.5794.205
Abstract
Raised fasting blood lactate levels were observed in diabetic patients on phenformin in therapeutic dosage. After an intravenous glucose load this effect was exaggerated and the lactate/pyruvate ratio increased. Withdrawal of the drug led to normal blood lactate levels and a fall in the lactate/pyruvate ratio.Keywords
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